Update : its been 7 days since my very 1st Xeomin injections, and it really does take a few to several days to fully kick in! at around day 3, I assumed it was as good as it would get, but it wasn't. I actually noticed the biggest change from day 5 thru 7 ! and it's hard to believe how much difference just a few days can make (without wrinkling, crinkling, and squinting). My forehead & between my eyebrows looks so smooth already! the only regret I have is not doing it a year or 2 ago.