Are you a hobby brewer? An aspiring hobby brewer? Operating a brewery? Do you just like the smell of grains? You should probably be checking out Toronto Brewing.
If you don't have a car, the location is absolutely super inconvenient. It's not as far as Manitoba, and the TTC does service the area. As a carshare user I plan my trips to the shop around my vehicle usage. If you own a car or have regular access to one then it's obviously no big deal. If you're going to buy equipment you'll need a vehicle anyway. Alternatively, you can always order everything off their website and they offer a wide range of delivery options.
Ultimately, the selection of grains to use in beer making, plus the wide variety of hops varietals and yeast strains offered more than make up for the industrial park location. The owners also offer workshops every few weeks that you can attend and learn more about brewing where you'll brew a batch together and sample some beers that others had already created.
I've been brewing for 6-7 years to date and as far as supply shops go for this stuff, Toronto Brewing is one of the best. Most of the critical reviews I've read seem to be people with unrealistic expectations and/or just feel entitled. Here they offer all the equipment you could need (plus lots more you don't but might want anyway). They have an inventory of product so you can make things from scratch, or you can buy things in kit forms. Their staff is super super knowledgeable and easy going. If you have questions they'll have answers (or at least try). If you don't have questions, then experiment!