My friend brought me to this shrine not only because I am Buddhist, but because she enjoys it so much. The last thing I expected to see behind Serendipity was a Buddhist shrine and if you didn't know it was here, you would definitely miss it as you cannot see it from the strip.
The Shrine has four sides and is beautifully crafted with the most precious metals. There is an incense box and matches on the right and a donation box on the left. There isn't any signage on the donation box, so don't try to put your matches in there.
The Shrine is a stark contrast from the busy life of the Strip and it seems that when you're there, the Strip doesn't exist. This may be why you cannot see it from the Strip and have to go "find" it.