There is a lot to like about Case Western. They have wonderful programs. A very engaged smaller student population. The campus is very pretty and easy to navigate. More and more retail and restaurants and popping up in and around university circle, Student housing is modernish...
That being said this area is still a tad bit rough and I would say you might use a bit of caution at night. It is your classic open urban campus within the city...as opposed to a place like Tufts that is totally encapsulated in its own Quad.
Never the less ranked 33 in the US....Case Western is an amazing University!