Club Cafe can be a great little venue.
The sound quality is hit or miss. The last show I went to the band ended up berating the sound guy the whole time.
As a previous reviewer mentioned, if you don't want to stand or have an obstructed view, get to the show early, especially if it's a well-known national act.
One great benefit of Club Cafe is their Yuengling special. All day every day, $2.50 including the dreaded drink tax.
Go to Club Cafe for its intimate size which is best suited for small bands and especially folk musicians. If you're seeing a band with more than 3 members, bring some earplugs. Luckily, the reasonable entry and cheap yuengling make this a great opportunity to check out new-to-you bands on the south side.