If you're going to do an after hours in this town, this is where to go. Legit music that goes darker and deeper than what you'll find in the big clubs on the Strip, a very industry-heavy crowd that takes full advantage of the cheap bottles.
When the weather is nice, the patio here is one of the nicest spots in town to enjoy a breather from the beats and a little civilized conversation.
The one issue I have with the Artisan - and it's a big one - is that the "dancefloor" is also the thoroughfare to get from pretty much anywhere in the building to anywhere else in the building. So you can't dance without people having to walk around you, and you have to walk across the dance floor whenever you want to move anywhere.
Other than that, this is a solid nightlife option in a really unique venue.