If you're in the mood to spend a lot of money on some running shoes, then Omega is the spot for you. That said, they seem very knowledgeable. When my daughter started getting some foot pain after working out on the treadmill at the gym, her doctor suggested giving one of these higher end shoe stores a first shot.
So we did. The two ladies who helped us really seemed to know what they were talking about. Whether or not they really did know it, or they were just good at giving us the run around (pun!), I don't know for sure. But my daughter now has some $120 shoes and she's back in the gym.
I'd suggest getting your first pair here and once you know what's good, you might be able to find them much less expensively on Amazon or Zappos.