I've been to Stand Up Live twice in the past month, first for the Sklar Brothers and then this past weekend for Stephen Rannazzisi. Both were great shows and it seems like Stand Up Live is getting many more big acts. I'll definitely return to this venue in the future for some of my favorite comedians, but I will always go to the early shows which start at 7:30pm and the doors open at 6:30pm.
When I went to the late show for the Sklar Brothers in December it started late and waiting in that line sucks. I went to the early Friday show for Stephen Rannazzisi and there was no line and we got a better seat at center stage. As others have mentioned, there is a two drink minimum, but that is pretty standard for most comedy clubs, so I wouldn't complain. I've also tried the pretzels with cheese dip and the chicken tenders. Both were great and I would get them again.
My only issue with this place (and it's been mentioned in many other reviews) is the crammed seating at the tables in front of the stage. They really need to remove some of the tables to allow the patrons to be more comfortable and not struggle to watch the show. Next time I go with friends I am considering getting one of the high top tables in the back to be more comfortable since I don't really care about being up close to the stage.
Another tip is to park in the garage at City Scape since the first three hours are free with a validation from Stand Up Live. After that it is only $2 per hour.
Before the show I highly recommend going to Copper Blues next door for dinner and drinks. The burgers are awesome and they have about 60 beers on tap. I'll be posting a review for them soon!