Go big or go home! This mall has tons of stores that you might not get at your local mall. There's something for everybody. I think most of the stores here definitely cater towards the fashionistas Vegas style.
If you stay across the street at the Wynn or the Venetian, its an easy walk. Parking is not too terrible if you can find a spot. I would say, if you can't find something at say, Ceasar's, the Wynn, or at your Hotel then definitely come by here.
I know the ladies would love the affordable Forever 21 and its pretty large and in charge. There is a Zara, one of my favorite stores, woohoo! There's a Japanese and British store that I know you can't get at your local mall, so that would make it worth dropping by.
Just another activity to do when you crash in Vegas.