Bed Bugs!
I checked in for one night after a long day of business meetings. My reservation had requested a down free room but the front desk had told me that I had been assigned a handicap room and reassigned me to a regular room. It was late and when I got into the room I found down pillows and comforter. I stripped them off the bed and slept with sheets and the accessory pillow. The next morning it had several bites on my arm that I assumed were mosquito bites, but as the day progressed they became large and swollen. When I got home I consulted a medical professional who determined they were likely bed bug bites. Definitely not staying there again when I visit my client in the area