Since I travel almost exclusively with US Airways, CLT (their main hub) is a frequent stop and I've been flying in/out of there for roughly 4 years now.
Planes usually run smoothly here no matter what section of the airport I'm flying out of. I've gone both domestic and international without a hassle. If you have status with US Airways the fast track on the security line is a god send.
The restaurants are good with some lively bars. The airport itself has a very open feel to it, littered with comfortable rocking chairs should you ever want to sit a spell. Shopping's decent if you're into that sort of thing. It could do with more electrical outlets for the business travelers, but otherwise it's a solid place.