The best Wine & Spirits in Pittsburgh, which isn't saying much as Pittsburgh is so behind with everything! Not to mention the PA Liquor Control Board controls everything in PA so there's no competition. The prices are more expensive in PA Wine & Spirits stores compared to other states I've been to where you can by liquor in your local grocery store.
This location sits on the site of the old Yellow Cab Company garage. It is on the second level of the building next to Borders Books. They carry just about every kind of wine or liquor you can think of. My only complaint is that if your looking for something popular they are always out of it. If it's on sale, it's sold out! For a store this large you would think they would have a better stock of liquor.
I can't speak on the wine selection as I don't drink it but, my wife loves Moscato and can always find it in a few different brands at this location.
Customer service is usually pretty good and there's always someone from a different liquor company in the store offering samples.
Insider Tip: This is one of the few Wine & Spirits stores open on Sundays.