On the positive side: the Microsoft Store de-crapifies your computer. If you buy an HP, for example, all of the HP installed useless add-ons are gone. You don't have to guess which ones to remove.
Real life experience is not that great. A friend was sold two low end little Asus Windows 10 tablet/keyboard devices last December. He bought them as Christmas gifts and was also talked into "Full Office" for each device. These were sold to him as full blown little computers, and they were not cheap.
One of the two tablets was used two or three times and decided to not take a charge anymore. It went back to the Microsoft Store who sent it to Asus. It was gone for weeks. When it came back, it was just as dead as before and would not charge. The Store service people obviously didn't even bother to turn it on. He asked for his money back and was told it had been too long. Exchange then? Nope, it was no longer carried. What they did offer was a store credit on a bigger computer that was "worth $800". It would take an hour or so to setup. It took 6 hours. (has anybody ever calculated productivity time lost on Microsoft Updates?) The new computer was also on sale for $699 in the store and at competitors, so not worth $800.
My friends were truly taken advantage of at the Microsoft Store. They blamed the manufacturer, Asus. Maybe, but Microsoft Service was the no-value-added middleman with an up-sale scheme at the end.