Food wise, I have had better. Nothing I've had on the menu across all the locations, including this "flagship" one, has impressed me in the least. I would equate the food to overpriced bar food trying way too hard to be more upscale than it actually is.
Beers on the other hand, that's a different story as I have yet to not like any of their brews. From seasonal to regulars, if you like beer, you should at least stop by a Great Dane location for beer alone. Sure, it's a bigger operation, but it's definitely better than the local brewpub in my hometown which seems to have a beer which is absolute crap every fourth or fifth brew on the list.
Basically: go for the beers, eat the food out of convenience.