Suite is the best dance club in Uptown and is amongst the best in Charlotte. The few times that I have been there, the djs have been between rock-solid and fantastic. Furthermore, people actually go there to dance (as opposed to standing around the dance floor - posing and fronting). It also has a cool balcony -- which particularly in the fall -- is a great place to lounge.
I will say that I don't like waiting in long lines and when I see them forming around Suite, I exit stage-right and go elsewhere. (Because, at the end of the day, I didn't drive to Uptown to spend all night in line, yo.)